Bilateral Testicular Mass Presenting as a Rare Manifestation of Extramedullary Plasmacytoma on 18F-FDG PET/CT.

Civan C., Apaydin Arikan E., Has Simsek D., Sanli O., Kuyumcu S.

Clinical nuclear medicine, vol.47, no.3, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.1097/rlu.0000000000004043
  • Journal Name: Clinical nuclear medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Keywords: extramedullary plasmacytoma, FDG, PET/CT, testicular mass, testicular plasmacytoma
  • Istanbul University Affiliated: Yes


We present the case of a 48-year-old man diagnosed with metastatic Ewing sarcoma who was referred for F-18-FDG PET/CT for treatment response evaluation following chemoradiotherapy. The patient also had complaints of new-onset testicular swelling at the time of imaging. Although the metastatic bone disease showed a complete metabolic response to treatment, F-18-FDG PET/CT demonstrated significantly increased metabolic activity in bilateral testicular mass. Consequently, the patient underwent bilateral orchiectomy, and histopathologic examination revealed bilateral testicular plasmacytoma, a rare manifestation of extramedullary plasmacytoma.