Effect of Interferon alfa-2a Treatment on Adaptive and Innate Immune Systems in Patients With Behcet Disease Uveitis

Albayrak O., Oray M., Can F., Kirimli G. U., Gül A., Tugal-Tutkun I., ...More

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, vol.60, no.1, pp.52-63, 2019 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 60 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.1167/iovs.18-25548
  • Journal Name: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.52-63
  • Keywords: interferons, Behcet disease, uveitis, adaptive, innate, REGULATORY T-CELLS, TOLL-LIKE RECEPTORS, FLUORESCEIN ANGIOGRAPHY, EXPRESSION, POSTERIOR, TH17, STANDARDIZATION, RECOMMENDATIONS, IMBALANCE, RESPONSES
  • Istanbul University Affiliated: Yes

Abstract

PURPOSE. To investigate the effect of interferon alfa-2a on T regulatory (Treg) cells, T helper 17 (Th17) cells, and expression of Toll-like receptors (TLRs) in Behcet disease (BD) patients with uveitis.