Synthesis and antiviral activity evaluation of some cyclohexylidenehydrazide derivatives of 1,3-thiazole core


Ulusoy Guzeldemirci N. , Pehlivan E., Halamoglu Z., Kocabalkanli A.

MARMARA PHARMACEUTICAL JOURNAL, cilt.20, sa.2, ss.207-215, 2016 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Konu: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.12991/mpj.20162019913
  • Dergi Adı: MARMARA PHARMACEUTICAL JOURNAL
  • Sayfa Sayıları: ss.207-215

Özet

Some novel cyclohexylidenehydrazide derivatives carrying five membered heterocyclic ring, 1,3-thiazole were synthesized to investigate their antiviral (including anti-HIV) activity against diverse DNA and RNA viruses in CRFK, HeLa, HEL, MDCK, Vero and MT4 cell cultures. None of the compounds was active against any of the DNA or RNA viruses at 100 mu M.