MAPK overexpression is associated with anthracycline resistance and increased risk for recurrence in patients with triple-negative breast cancer

Eralp, Y.; Derin, D.; Ozluk, Mesude; Yavuz, Erdem; Guney, N.; Saip, P.; Muslumanoglu, M.; Igci, A.; Kucucuk, S.; Dincer, M.; Aydiner, A.; Topuz, E.

doi:10.1093/annonc/mdm522

MAPK overexpression is associated with anthracycline resistance and increased risk for recurrence in patients with triple-negative breast cancer

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Eralp Y., Derin D., Ozluk Y., Yavuz E., Guney N., Saip P., ...More

ANNALS OF ONCOLOGY, vol.19, no.4, pp.669-674, 2008 (SCI-Expanded)

Publication Type: Article / Article
Volume: 19 Issue: 4
Publication Date: 2008
Doi Number: 10.1093/annonc/mdm522
Journal Name: ANNALS OF ONCOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.669-674
Keywords: chemoresistance, EGFR, MAPK, prognosis, triple-negative breast cancer, ACTIVATED PROTEIN-KINASE, BASAL-LIKE SUBTYPE, PROGNOSTIC-SIGNIFICANCE, EXPRESSION PATTERNS, CARCINOMAS, PHENOTYPE, RECEPTOR, PATHWAYS, SURVIVAL
Istanbul University Affiliated: Yes

Abstract

Background: Triple-negative breast cancer is estimated to account for 15%-20% of all patients with breast cancer and is considered as a prognostically unfavorable subset. The aim of this study is to evaluate the prognostic impact of various molecular factors in patients with triple-negative breast cancer.