Investigation of Bosentan's Effects on Pulmonary Contusion Created by Blunt Thoracic Trauma in Rats

Gercel G., Aksu B., Ozkanli S., UZUN H., Aksu F., Ozatman E., ...More

EUROPEAN JOURNAL OF PEDIATRIC SURGERY, vol.30, no.1, pp.71-78, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.1055/s-0039-1697908
  • Journal Name: EUROPEAN JOURNAL OF PEDIATRIC SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.71-78
  • Istanbul University Affiliated: Yes

Abstract

Introduction Bosentan is an endothelin-1 receptor antagonist with anti-inflammatory, antioxidant, and antiproliferative effects. We aimed to evaluate its effects on lung tissue in a pulmonary contusion (PC) model.