Aberrant Methylation Profile and Microsatellit Instability in Turkish Sporadic Colorectal Carcinoma


Ekmekci C. G., Gulluoglu M., Kapran Y., Dizdaroglu F., ÖZBEK U.

BEZMIALEM SCIENCE, vol.7, no.2, pp.86-94, 2019 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.14235/bas.galenos.2018.2456
  • Journal Name: BEZMIALEM SCIENCE
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.86-94
  • Istanbul University Affiliated: Yes

Abstract

Objective: Genomic DNA obtained from paraffin blocks of the intended colorectal cancer cases was evaluated for promoting colorectal cancer by investigating the promoter methylation of 6 different gene promoter regions and microsatellite instability.