Akademik Veri Yönetim Sistemi
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, cilt.344, 2026 (SCI-Expanded, Scopus)
Iron is a vital micronutrient for human physiology, yet its imbalance—whether as a deficiency or in excess—can pose significant health risks. Traditional detection methods for Fe3+ ions often face challenges, prompting the development of less toxic and more stable fluorescent probes. In this study, a novel hybrid system was engineered, integrating an organic fluorescent dye (BODIPY) with inorganic silica nanoparticles (SNPs) for the sensitive and selective detection of Fe3+ ions. A BODIPY scaffold was selected as a signalling reporter unit and covalently bonded to silica nanoparticles. The resulting probe, BOD–SNP, exhibited a “turn-on” fluorometric response with high sensitivity (LOD = 1.3 μM). Notably, BOD–SNP effectively detected Fe3+ ions in complex matrices, including water and beverage samples. It is also an appropriate system for colorimetric detection of Fe3+ under a fluorescence lamp using a smartphone based on RGB analysis. This is one of the rare studies exploring the application of silica nanoparticle-based systems for the fluorometric ‘turn-on’ detection of Fe3+ ions, paving the way for advanced analytical applications.