Influence of conversion from calcineurin inhibitors to everolimus on fibrosis, inflammation, tubular damage and vascular function in renal transplant patients

Alpay, Nadir; Ozkok, Abdullah; Caliskan, Yasar; Akagun, Tülin; Cinar, Suzan; Deniz, Günnur; Sariyar, Muzaffer; Yildiz, Alaattin

doi:10.1007/s10157-014-0939-4

Influence of conversion from calcineurin inhibitors to everolimus on fibrosis, inflammation, tubular damage and vascular function in renal transplant patients

Atıf İçin Kopyala

Alpay N., Ozkok A., Caliskan Y., Akagun T., Cinar S., Deniz G., ...Daha Fazla

CLINICAL AND EXPERIMENTAL NEPHROLOGY, cilt.18, sa.6, ss.961-967, 2014 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 18 Sayı: 6
Basım Tarihi: 2014
Doi Numarası: 10.1007/s10157-014-0939-4
Dergi Adı: CLINICAL AND EXPERIMENTAL NEPHROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.961-967
İstanbul Üniversitesi Adresli: Evet

Özet

Conversion from calcineurin inhibitor (CNI) to mTOR inhibitors may reduce and even halt the progression of chronic allograft dysfunction (CAD) which is the most important cause of renal allograft loss. We aimed to investigate the effects of conversion from CNI to everolimus on parameters of fibrosis, inflammation, glomerulotubular damage and vascular functions in renal transplant recipients.