Effects of parsley (Petroselinum crispum) on the liver of diabetic rats: a morphological and biochemical study

Bolkent S., Yanardag R., Ozsoy-Sacan O., Karabulut-Bulan O.

PHYTOTHERAPY RESEARCH, cilt.18, sa.12, ss.996-999, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 12
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1002/ptr.1598
  • Dergi Adı: PHYTOTHERAPY RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.996-999
  • Anahtar Kelimeler: parsley, Petrosclinum crispum, diabetes mellitus liver, rat, HYPOGLYCEMIC ACTIVITY, BLOOD-GLUCOSE, PLANTS
  • İstanbul Üniversitesi Adresli: Evet

Özet

Parsley is used by diabetics in Turkey to reduce blood glucose. The present study aims to investigate both the morphological and biochemical effects of parsley on liver tissue. Rat hepatocytes were examined by light and electron microscopy. Degenerative changes were observed in the hepatocytes of diabetic rats. These degenerative changes were significantly reduced or absent in the hepatocytes of diabetic rats treated with parsley. Blood glucose levels, alanine transaminase and alkaline phosphatase were observed to be raised in diabetic rats. Diabetic rats treated with parsley demonstrated significantly lower levels of blood glucose, alanine transaminase and alkaline phosphatase. The present study suggests that parsley demonstrates a significant bepatoprotective effect in diabetic rats. Copyright (C) 2004 John Wiley Sons, Ltd.