A Case of Isolated Nocardia asteroides Brain Abscess in a Kidney Transplant Recipient


OZTURK S., TUFAN F., ALISIR S., GORCIN S., GUVEN D., Cagatay A. A., ...Daha Fazla

Transplantation Proceedings, cilt.38, sa.9, ss.3121-3124, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 9
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.transproceed.2006.08.109
  • Dergi Adı: Transplantation Proceedings
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3121-3124
  • İstanbul Üniversitesi Adresli: Evet

Özet

Because of the immunosuppressive drugs used after organ transplantation, there is an increased rate of certain infections and malignancies. Nocardia brain abscess is a rare condition, seen most commonly among immunocompromised patients. It may be confused with intracranial tumors and requires long-term combined antibiotic therapy after drainage. Case Report: A patient who underwent renal transplantation because of end-stage renal disease of unknown origin was shown to have a nocardial brain abscess while she was taking immunosuppressive drugs. The patient was given combined antibiotics and the abscess drained surgically. After 2 months, antibiotic therapy was continued with one drug. Neither a complication nor clinical or radiological sequelae occurred in this patient. Conclusions: When central nervous system findings are observed in renal transplant recipients, nocardial brain abscess must be considered in the differential diagnosis. Recommended treatment duration is 6 to 12 months with frequent imaging. © 2006 Elsevier Inc. All rights reserved.