Four rabbits received human derived HA to their left tibias. After 16 weeks bioglass was implanted to their right tibias. After other 16 weeks bone scintigraphies were taken with Tc-99m-MDP. Three phase bone scan images showed no evidence of inflammation and superior vascularization rates at implantation sites. In this study, bioglass demonstrated higher uptake of Tc-99m-MDP comparing to HA, suggesting a higher vascularization rate and better osseointegration.