Gene Regulation of MHC Class-I and MHC Class-II


Karatas S., Savran Oguz F.

TURKISH JOURNAL OF IMMUNOLOGY, cilt.8, sa.3, ss.144-156, 2020 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 8 Konu: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.25002/tji.2020.1364
  • Dergi Adı: TURKISH JOURNAL OF IMMUNOLOGY
  • Sayfa Sayıları: ss.144-156

Özet

Introduction: Peptides obtained by processing intracellular and extracellular antigens are presented to T cells to stimulate the immune response. This presentation is made by peptide receptors called major histocompatibility complex (MHC) molecules. The regulation mechanisms of MHC molecules, which have similar roles in the immune response, especially at the gene level, have significant differences according to their class.