EUROPEAN STROKE JOURNAL, vol.2, no.2, pp.116-125, 2017 (ESCI)
Background: Worldwide, about 1.3 million annual ischaemic strokes (IS) occur in adults aged <50 years. Of these early-onset strokes, up to 50% can be regarded as cryptogenic or associated with conditions with poorly documented causality like patent foramen ovale and coagulopathies.