Saniculoside N from Sanicula europaea L.

Arda N., Goren N., Kuru A., Pengsuparp T., Pezzuto J., Qiu S., ...More

JOURNAL OF NATURAL PRODUCTS, vol.60, no.11, pp.1170-1173, 1997 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 60 Issue: 11
  • Publication Date: 1997
  • Doi Number: 10.1021/np9701790
  • Journal Name: JOURNAL OF NATURAL PRODUCTS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1170-1173
  • Istanbul University Affiliated: Yes

Abstract

Extracts from the aerial parts of Sanicula europaea L. were investigated for their anti-HN activity, and the 50% ethanolic extract was shown to exhibit the highest activity. A new triterpene saponin glycoside, 21 beta-(angeloyloxy)-3-O-[beta-D-arabinopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->3)-beta-D-glucuronopyranosyl propyl ester]-3 beta,15,16,22 alpha,28 beta-pentahydroxy-Delta(12)-oleanene, saniculoside N (1), in addition to the known phenolic acids, rosmarinic acid (2), and caffeic acid(3) were isolated as major components. Rosmarinic acid was established as the principal active substance.