Primary cutaneous immunocytoma/marginal zone B-cell lymphoma: A case with unusual course

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Demirkesen C., Tuzuner N., Su O., Esckazan A., Soysal T., Onsun N.

AMERICAN JOURNAL OF DERMATOPATHOLOGY, vol.26, no.2, pp.119-122, 2004 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 26 Issue: 2
• Publication Date: 2004
• Doi Number: 10.1097/00000372-200404000-00006
• Journal Name: AMERICAN JOURNAL OF DERMATOPATHOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.119-122
• Istanbul University Affiliated: No

Abstract

Although primary cutaneous immunocytoma/marginal zone B-cell lymphoma (PCI/MZBL) is considered as an indolent lymphoma with excellent prognosis, extracutaneous spread and even death due to disseminated disease have been reported. This is a case report of a PCI/MZBL showing dissemination to the regional lymph node and bone marrow, 22 months after the initial diagnosis. Furthermore, in the lymph node, there were focal areas of high-grade transformation. On the other hand, the bone marrow involvement displayed low-grade morphology. We suggest that it should be kept in mind that there is still a possibility of systemic involvement in PCI/MZBL.