Primary cutaneous immunocytoma/marginal zone B-cell lymphoma: A case with unusual course

Demirkesen C., Tuzuner N., Su O., Esckazan A., Soysal T., Onsun N.

AMERICAN JOURNAL OF DERMATOPATHOLOGY, cilt.26, ss.119-122, 2004 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 26 Konu: 2
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1097/00000372-200404000-00006
  • Sayfa Sayıları: ss.119-122


Although primary cutaneous immunocytoma/marginal zone B-cell lymphoma (PCI/MZBL) is considered as an indolent lymphoma with excellent prognosis, extracutaneous spread and even death due to disseminated disease have been reported. This is a case report of a PCI/MZBL showing dissemination to the regional lymph node and bone marrow, 22 months after the initial diagnosis. Furthermore, in the lymph node, there were focal areas of high-grade transformation. On the other hand, the bone marrow involvement displayed low-grade morphology. We suggest that it should be kept in mind that there is still a possibility of systemic involvement in PCI/MZBL.