Diagnostic Value of Strain Echocardiography, Galectin-3, and Tenascin-C Levels for the Identification of Patients with Pulmonary and Cardiac Sarcoidosis

Kul, Seref; Ozcelik, Hatice; Uyarel, Huseyin; KARAKUS, Gultekin; Guvenc, Tolga; Yalcinsoy, Murat; Asoglu, Emin; Kemik, Ahu; Tasal, Abdurrahman; Gungor, Sinem; KARAARSLAN, Ercan; Kart, Levent; Goktekin, Omer

doi:10.1007/s00408-014-9586-5

Diagnostic Value of Strain Echocardiography, Galectin-3, and Tenascin-C Levels for the Identification of Patients with Pulmonary and Cardiac Sarcoidosis

Kul S., Ozcelik H. K., Uyarel H., KARAKUS G., Guvenc T. S., Yalcinsoy M., ...More

LUNG, vol.192, no.4, pp.533-542, 2014 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 192 Issue: 4
Publication Date: 2014
Doi Number: 10.1007/s00408-014-9586-5
Journal Name: LUNG
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.533-542
Istanbul University Affiliated: Yes

Abstract

Cardiac involvement in sarcoidosis has been associated with poor prognosis. We evaluated myocardial contractility quantitatively in a cohort of pulmonary sarcoidosis (PS) patients with and without cardiac involvement. We also studied markers of fibrosis (tenascin-C [Tn-C] and galectin-3 [Gl-3]) as diagnostic tools for PS and cardiac sarcoidosis (CS).