We describe a patient with cerebellar ataxia of degenerative nature who was administered high-dose piracetam in a single-blind trial. Piracetam was demonstrated to be highly effective on tandem gait and gait ataxia in daily doses of 60 g. We suggest piracetam has a potential anti-ataxic effect in human cerebellar ataxia when used in considerably higher doses than those indicated for other purposes. (C) 2003 Movement Disorder Society.
We report on a patient with spontaneous and stimulus-
sensitive myoclonic jerks and dystonia of the right leg that
had been present since infancy. Magnetic resonance imaging
showed a linear area of gliosis confined to the left posterolateral
putamen. This is the first report of focal myoclonus-dystonia of
the lower limb secondary to a putaminal lesion.