Biological activity and chemical composition of the essential oil from the fruits of Ferula halophila Peşmen

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KÜRKÇÜOĞLU M., İŞCAN G., TOSUN F., MİSKİ M.

Acta Pharmaceutica Sciencia, cilt.61, sa.1, ss.81-90, 2023 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 61 Sayı: 1
  • Basım Tarihi: 2023
  • Doi Numarası: 10.23893/1307-2080.aps6106
  • Dergi Adı: Acta Pharmaceutica Sciencia
  • Derginin Tarandığı İndeksler: Scopus, EMBASE
  • Sayfa Sayıları: ss.81-90
  • Anahtar Kelimeler: Antibacterial, anticandidal, essential oil, Ferula halophila
  • İstanbul Üniversitesi Adresli: Evet

Özet

The hydrodistilled essential oils of the dried fruits of F. halophila Peşmen, an endemic species growing near Salt Lake in Central Anatolia, were analyzed by GC and GC-MS systems; 27 and 24 compounds representing 92.1% and 79.8% of the essential oils were characterized, respectively. The main component of the essential oils was identified as β-phellandrene. The antibacterial and anticandidal effects of the essential oils were determined by using partly modified CLSI methods M7-A7 and M27-A2, respectively. The essential oils from two specimens showed weak to moderate inhibitory effects on the tested pathogenic bacteria (MIC, 125-2000 µg/ mL) and Candida panels (MIC, 156-1250 µg/mL).