Behcet's disease patients with multiple sclerosis-like features: discriminative value of Barkhof criteria

AKMAN-DEMIR G., Mutlu M. O., KIYAT-ARAMER A., Shugaiv E., Kurtuncu M., Tugal-Tutkun I., ...More

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, vol.33, no.6, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 6
  • Publication Date: 2015
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Behcet's disease, MRI, white matter lesions, multiple sclerosis, NEUROLOGICAL INVOLVEMENT, CLINICAL CHARACTERISTICS, MRI FINDINGS
  • Istanbul University Affiliated: Yes


Objective. Behcet's disease (BD) is a systemic auto-inflammatory disorder of unknown cause, which may affect the central nervous system in around 5% of the patients [neuro-BD (NBD)], usually causing large lesions encompassing brainstem, diencephalon and basal ganglia regions. Occasionally NBD patients present with white matter lesions necessitating differential diagnosis from multiple sclerosis (MS). In this study, the efficacy of Barkhof criteria was tested in diagnostic differentiation of NBD and MS.