Hypovitaminosis D is Associated with Endothelial Dysfunction in Patients with Metabolic Syndrome

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Oruc C. U., Akpinar Y. E., Amikishiyev S., Uzum A. K., Salmaslioglu A., Gurdol F., ...More

CURRENT VASCULAR PHARMACOLOGY, vol.15, no.2, pp.152-157, 2017 (SCI-Expanded, Scopus)

• Publication Type: Article / Article
• Volume: 15 Issue: 2
• Publication Date: 2017
• Doi Number: 10.2174/1570161114666161003093443
• Journal Name: CURRENT VASCULAR PHARMACOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.152-157
• Istanbul University Affiliated: Yes

Abstract

Objectives: Recent research has shown that hypovitaminosis D may increase the risk of hypertension, vascular disease, diabetes mellitus, obesity and Metabolic Syndrome (MetS). Endothelial Dysfunction (ED) is one of the key components of MetS which is associated with an imbalance between vasoactive substances such as Nitric Oxide (NO) and Endothelins (ET). In this study, we assessed the association of 25(OH) D3 level with endothelial dysfunction and subclinical atherosclerosis in MetS patients.