BRONCHODILATING EFFECT OF INHALED AND INTRAVENOUS MAGNESIUM-SULFATE (COMPARED WITH AERESOL TERBUTALINE)

TETIKKURT C., KOCYIGIT E., DISCI R.

MAGNESIUM-BULLETIN, cilt.14, sa.2, ss.49-52, 1992 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 2
  • Basım Tarihi: 1992
  • Dergi Adı: MAGNESIUM-BULLETIN
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.49-52
  • İstanbul Üniversitesi Adresli: Evet

Özet

The bronchodilating effect of intravenous magnesium sulfate (MgSO4) was studied in 25 asthmatic patients with mild to moderate bronchial reactivity. Subjects received, in random order, on separate days, 3 days apart, saline (NaCl) and MgSO4 inhalation. Spirometry was recorded on each test day before and 5 minutes after NaCl and MgSO4 inhalation. Neither NaCl nor MgSO4 were found to have a significant effect on spirometric measurements. Three days later the patients were administered with an intravenous infusion of saline placebo and 2 g Of MgSO4. Magnesium sulfate infusion rapidly relieved bronchoconstriction and produced significant improvement in lung function measurements.