Morphological Changes of Trichomonas vaginalis Treated by Ornidazole: An In-Vitro Study

Cakan H., Polat E. , Arda O., Cepni I., Dirican A., Sirekbasan S.

CLINICAL LABORATORY, cilt.62, ss.793-800, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 62 Konu: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.7754/clin.lab.2015.150731
  • Sayfa Sayıları: ss.793-800


Background: Nitroimidazoles, which are drugs that are used to effectively treat Trichomonas vaginalis, alter the structure of the T. vaginalis cell membrane, penetrate into its cytoplasm and nucleus and block cellular metabolism. In this study, we observed the morphological changes that occurred in T. vaginalis during in vitro exposure to 1.3 mu g/mL of ornidazole at various time intervals ranging from 10 minutes to 10 hours.