Morphological Changes of Trichomonas vaginalis Treated by Ornidazole: An In-Vitro Study


Cakan H., Polat E., Arda O., Cepni I., Dirican A., Sirekbasan S.

CLINICAL LABORATORY, cilt.62, sa.5, ss.793-800, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 62 Sayı: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.7754/clin.lab.2015.150731
  • Dergi Adı: CLINICAL LABORATORY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.793-800
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Nitroimidazoles, which are drugs that are used to effectively treat Trichomonas vaginalis, alter the structure of the T. vaginalis cell membrane, penetrate into its cytoplasm and nucleus and block cellular metabolism. In this study, we observed the morphological changes that occurred in T. vaginalis during in vitro exposure to 1.3 mu g/mL of ornidazole at various time intervals ranging from 10 minutes to 10 hours.