Cytotoxic Effects of Some Flavonoids and Imatinib on the K562 Chronic Myeloid Leukemia Cell Line: Data Analysis Using the Combination Index Method


Kalmdemirtas F. D., Birman H., Candoken E., Gazioglu S. B., Melikoglu G., Kuruca S.

BALKAN MEDICAL JOURNAL, vol.36, no.2, pp.96-105, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.4274/balkanmedj.galenos.2018.2017.1244
  • Journal Name: BALKAN MEDICAL JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.96-105
  • Keywords: Cell culture, cell cytotoxicity, flavonoids, imatinib mesylate, K562 cells, P-GLYCOPROTEIN, EXPERIMENTAL-DESIGN, CANCER, APOPTOSIS, RESISTANCE, ANTIOXIDANTS, MODULATION, APIGENIN
  • Istanbul University Affiliated: Yes

Abstract

Background: Flavonoids are natural compounds with antioxidant, anticarcinogenic, and anti-inflammatory effects.