A case of hynomelanosis of Ito accompanied by unilateral abnormal limb overgrowth and delayed speech

Ozcetin M. , Kılıç A., Cag Y., Bilgili F. , Aksoy B.

NORTHERN CLINICS OF ISTANBUL, vol.7, no.1, pp.71-73, 2020 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.14744/nci.2018.86648
  • Journal Indexes: Emerging Sources Citation Index, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.71-73


Hypomelanosis of Ito (HI) is characterized by unilateral or bilateral hypopigmented skin lesions and usually presents as a multisystemic disorder. Skin lesions may develop in different textures, such as linear, whorled, or patchy, and are often accompanied by abnormalities of the central nervous system, skeletal system, eyes, and teeth. HI is associated with sporadic gene mutations but not gender. Presentation of the current case may be of use in reminding practitioners of the common extracutaneous findings of HI, along with some rare manifestations, such as delayed speech and asymmetric limb growth.