The protective role of melatonin in experimental hypoxic brain damage
PEDIATRICS INTERNATIONAL, vol.47, no.4, pp.434-439, 2005 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 47 Issue: 4
- Publication Date: 2005
- Doi Number: 10.1111/j.1442-200x.2005.02085.x
- Journal Name: PEDIATRICS INTERNATIONAL
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.434-439
- Istanbul University Affiliated: No
Abstract
Background: It is known that oxygen-derived free radicals play an important role in the pathogenesis of brain injury. Melatonin is a powerful scavenger of the oxygen free radicals. In this study, the protective effect of melatonin against the damage inflicted by reactive oxygen species during brain hypoxia was investigated in newborn rats using biochemical parameters.