Research Information System
Turkish Archives of Pediatrics, vol.57, no.5, pp.566-568, 2022 (Scopus, TRDizin)
Objective: Neurofibromatosis 1 is an autosomal dominant inherited tumor susceptibility syn-drome. Individuals with neurofibromatosis 1 have a 4-5 times increased risk of malignancy compared to the general population. Central nervous system and soft tissue tumors are common non-hematological malignancies in individuals with neurofibromatosis 1. Although the association of leukemia and non-Hodgkin lymphoma as hematologic malignancies in neurofi-bromatosis 1 has been reported frequently in the literature in these individuals, association with Hodgkin lymphoma has been reported very rarely. Materials and Methods: We presented a patient with neurofibromatosis 1 who further developed Hodgkin lymphoma and reviewed the literature. Conclusion: Although rare, Hodgkin lymphoma can develop in individuals with neurofibroma-tosis 1. Hodgkin lymphoma should be kept in mind in cervical/supraclavicular lymphadeno-megalies when evaluating patients with neurofibromatosis 1.