Neurofibromatosis Type I and Hodgkin Lymphoma: Case Report and Review of the Literature
Turkish Archives of Pediatrics, cilt.57, sa.5, ss.566-568, 2022 (Scopus, TRDizin)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 57 Sayı: 5
- Basım Tarihi: 2022
- Doi Numarası: 10.5152/turkarchpediatr.2022.22004
- Dergi Adı: Turkish Archives of Pediatrics
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.566-568
- Anahtar Kelimeler: cancer predisposition, Hodgkin lymphoma, Neurofibromatosis, pediatrics
- İstanbul Üniversitesi Adresli: Hayır
Özet
Objective: Neurofibromatosis 1 is an autosomal dominant inherited tumor susceptibility syn-drome. Individuals with neurofibromatosis 1 have a 4-5 times increased risk of malignancy compared to the general population. Central nervous system and soft tissue tumors are common non-hematological malignancies in individuals with neurofibromatosis 1. Although the association of leukemia and non-Hodgkin lymphoma as hematologic malignancies in neurofi-bromatosis 1 has been reported frequently in the literature in these individuals, association with Hodgkin lymphoma has been reported very rarely. Materials and Methods: We presented a patient with neurofibromatosis 1 who further developed Hodgkin lymphoma and reviewed the literature. Conclusion: Although rare, Hodgkin lymphoma can develop in individuals with neurofibroma-tosis 1. Hodgkin lymphoma should be kept in mind in cervical/supraclavicular lymphadeno-megalies when evaluating patients with neurofibromatosis 1.