Metastatic Poorly Differentiated Thyroid Cancer With Heterogeneous Distribution of F-18-FDG, Ga-68-DOTATATE, and Ga-68-PSMA on PET/CT

Civan C., Isik E. G., Simsek D.

CLINICAL NUCLEAR MEDICINE, cilt.46, sa.4, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Editöre Mektup
  • Cilt numarası: 46 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1097/rlu.0000000000003362
  • Dergi Adı: CLINICAL NUCLEAR MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Anahtar Kelimeler: F-18-FDG, Ga-68-PSMA, Ga-68-DOTA, poorly differentiated thyroid cancer, RECEPTOR RADIONUCLIDE THERAPY, CARCINOMAS
  • İstanbul Üniversitesi Adresli: Evet

Özet

We present a case of a 55-year-old man with a history of poorly differentiated metastatic thyroid cancer, which is rare and shows aggressive behavior. The patient had radioactive iodine-negative multiple metastasis on F-18-FDG PET/CT, therefore Ga-68-DOTATATE and Ga-68-PSMA PET/CT were performed whether an opportunity exist for DOTATATE or PSMA-directed radionuclide therapy. Different patterns of tumoral uptakes were detected on F-18-FDG, Ga-68-DOTATATE, and Ga-68-PSMA PET/CT, as a demonstration of tumor heterogeneity.