Aleppicatines A and B from Euphorbia aleppica

Oksuz S., Gurek F., Lin L., Gil R., Pezzuto J., Cordell G.

PHYTOCHEMISTRY, vol.42, no.2, pp.473-478, 1996 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 2
  • Publication Date: 1996
  • Doi Number: 10.1016/0031-9422(95)00889-6
  • Title of Journal : PHYTOCHEMISTRY
  • Page Numbers: pp.473-478


Two new pentacyclic diterpene polyesters, aleppicatine A and B, have been isolated from the acetone extract of the whole plant of Euphorbia aleppica, in addition to five known cycloartane-type triterpenes (24-methylenecycloartanol, cyclolaudenol, cycloart-25-en-3 beta-ol-24-one, cycloart-22-en-3 beta,25-diol and cycloart-25-en-3 beta,24-diol), scopoletin, kaempferol and 4-hydroxybenzoic acid and its methyl ether. The structures of the new compounds and their hydrolysis products have been extensively characterized by high-field NMR spectroscopic methods, including 2D NMR techniques.