Effect of a combination of mometasone furoate, levofloxacin, and retinyl palmitate with an in situ gel-forming nasal delivery system on nasal mucosa damage repair in an experimental rabbit model


Aksoy F., DOĞAN R., ÖZTURAN O., Altuntas E. , Yener F. G. , TOPÇU G., ...More

BIOMEDICINE & PHARMACOTHERAPY, vol.96, pp.603-611, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 96
  • Publication Date: 2017
  • Doi Number: 10.1016/j.biopha.2017.10.023
  • Journal Name: BIOMEDICINE & PHARMACOTHERAPY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.603-611
  • Keywords: Mometasone furoate, Levofloxacin, Retinyl palmitate, Nasal mucosal damage, in situ gel, ENDOSCOPIC SINUS SURGERY, MAXILLARY SINUS, ACID, REGENERATION, VENLAFAXINE, REMOVAL, SPRAY, SHEEP

Abstract

Background: In this study a combination of Mometasone Furoate (MF) + Levofloxacin hemihydrate (LH) + Retinyl palmitate (RP) with an in situ gel-forming delivery system was evaluated at different stages of nasal mucosal damage repair in a rabbit maxillary sinus model.