Frequency and prognostic impact of antibodies to aquaporin-4 in patients with optic neuritis

Jarius, Sven; Frederikson, Jette; Waters, Patrick; Paul, Friedemann; Akman-Demir, Gulsen; Marignier, Romain; Franciotta, Diego; Ruprecht, Klemens; Kuenz, Bettina; Rommer, Paulus; Kristoferitsch, Wolfgang; Wildemann, Brigitte; Vincent, Angela

doi:10.1016/j.jns.2010.07.011

Frequency and prognostic impact of antibodies to aquaporin-4 in patients with optic neuritis

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Jarius S., Frederikson J., Waters P., Paul F., Akman-Demir G., Marignier R., ...More

JOURNAL OF THE NEUROLOGICAL SCIENCES, vol.298, pp.158-162, 2010 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 298
Publication Date: 2010
Doi Number: 10.1016/j.jns.2010.07.011
Title of Journal : JOURNAL OF THE NEUROLOGICAL SCIENCES
Page Numbers: pp.158-162

Abstract

Background: Antibodies to aquaporin-4 (AQP4-Ab) are found in 60-80% of patients with neuromyelitis optica (NMO), a severely disabling inflammatory CNS disorder of putative autoimmune aetiology, which predominantly affects the optic nerves and spinal cord.