Frequency and prognostic impact of antibodies to aquaporin-4 in patients with optic neuritis


Jarius S., Frederikson J., Waters P., Paul F., Akman-Demir G., Marignier R., ...More

JOURNAL OF THE NEUROLOGICAL SCIENCES, vol.298, pp.158-162, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 298
  • Publication Date: 2010
  • Doi Number: 10.1016/j.jns.2010.07.011
  • Title of Journal : JOURNAL OF THE NEUROLOGICAL SCIENCES
  • Page Numbers: pp.158-162

Abstract

Background: Antibodies to aquaporin-4 (AQP4-Ab) are found in 60-80% of patients with neuromyelitis optica (NMO), a severely disabling inflammatory CNS disorder of putative autoimmune aetiology, which predominantly affects the optic nerves and spinal cord.