The effect of LKB1 on the PI3K/Akt pathway activation in association with PTEN and PIK3CA in HNC

Ekizoglu, Seda; Dogan, S.; Ulker, D.; Seven, D.; Gozen, E.; Karaman, Emin; Buyru, Ayşe

doi:10.1111/coa.12427

The effect of LKB1 on the PI3K/Akt pathway activation in association with PTEN and PIK3CA in HNC

Ekizoglu S., Dogan S., Ulker D., Seven D., Gozen E. D., Karaman E., ...Daha Fazla

CLINICAL OTOLARYNGOLOGY, cilt.40, sa.6, ss.622-628, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 40 Sayı: 6
Basım Tarihi: 2015
Doi Numarası: 10.1111/coa.12427
Dergi Adı: CLINICAL OTOLARYNGOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.622-628
İstanbul Üniversitesi Adresli: Evet

Özet

Objective: PI3K/Akt signalling pathway is frequently activated in several types of cancer. However, activator molecules have not been analysed systematically in HNSCC. The aim of this study was to investigate upstream activators and inhibitors of this pathway.