Evaluation of Schlemm Canal Parameters Using Swept-Source Optical Coherence Tomography in Eyes That Underwent Keratoplasty


Bolac R., Ozcelik-Kose A., Imamoglu S., Yildiz E., Ozturk Y., Mangan M. S.

EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE, cilt.49, sa.9, ss.379-385, 2023 (SCI-Expanded, Scopus) identifier identifier identifier

Özet

Objectives: In this study, we aimed to evaluate Schlemm canal parameters using anterior segment swept-source optical coherence tomography in eyes that underwent keratoplasty and compare them with keratoconus and healthy control groups. Methods: The study included 32 patients who underwent penetrating keratoplasty or deep anterior lamellar keratoplasty once due to keratoconus and age-matched and sex-matched 20 keratoconus patients and 30 healthy controls. In all the patients, a single horizontal image centered on the central cornea was obtained from the nasal and temporal quadrants with low-intensity scanning to visualize Schlemm canal. Results: There was no statistically significant difference between the groups for age and gender (P>0.05). In the keratoplasty group, the area and diameter of Schlemm canal were 2.266 +/- 1.141 mu m(2) and 160.77 +/- 65.08 mu m, respectively, in the nasal quadrant and 2.62361.277 mu m(2) and 158.81 +/- 68.05 mu m, respectively in the temporal quadrant, which were statistically significantly lower compared with other groups (P<0.001 for all). There was no significant difference between the penetrating and deep anterior lamellar keratoplasty subgroups for Schlemm canal parameters. Conclusion: This is the first study to report anterior segment optical coherence tomography after surgery shows SC parameters that are, on average, less than age-matched and keratoconus controls.