Obstructive mechanical mitral valve thrombosis and gastric adenocarcinoma: A therapeutic dilemma

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Atıf İçin Kopyala

Karaayvaz E., DEMİRTAKAN Z. G., Sonsoz M. R., NALBANT A., BUĞRA M. Z.

TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, cilt.48, sa.8, ss.775-778, 2020 (ESCI)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 48 Sayı: 8
• Basım Tarihi: 2020
• Doi Numarası: 10.5543/tkda.2020.09406
• Dergi Adı: TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
• Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.775-778
• İstanbul Üniversitesi Adresli: Evet

Özet

Fibrinolysis is an option for the management of mechanical prosthetic valve thrombosis when surgery has prohibitive risks. Current guidelines suggest recombinant tissue plasminogen activator (not to exceed 100 mg) with unfractionated heparin. A low-dose (25 mg) alteplase regimen as treatment in patients with a high risk of bleeding warrants further research. This report describes the case of a 65-year-old woman with a history of mechanical prosthetic mitral valve replacement who was diagnosed with signet ring cell adenocarcinoma of the stomach and obstructive mechanical prosthetic thrombosis on echocardiogram. Details of challenging aspects of this case and the use of modified fibrinolytic therapy are provided.