Atıf İçin Kopyala
Ozhan G., Lochan R., Leathart J. B. S., Charnley R., Daly A. K.
PANCREAS, cilt.40, sa.8, ss.1289-1294, 2011 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
40
Sayı:
8
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Basım Tarihi:
2011
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Doi Numarası:
10.1097/mpa.0b013e31821fcc3b
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Dergi Adı:
PANCREAS
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.1289-1294
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Anahtar Kelimeler:
pancreatic cancer, COX-2, SNPs, LUNG-CANCER, COX-2 GENE, FUNCTIONAL POLYMORPHISMS, BREAST-CANCER, ESOPHAGEAL ADENOCARCINOMA, INFLAMMATORY RESPONSE, COMMON POLYMORPHISM, CHINESE POPULATION, CIGARETTE-SMOKING, CELL-CARCINOMA
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İstanbul Üniversitesi Adresli:
Evet
Özet
Objectives: DNA sequence variants in the cyclooxygenase-2 (COX-2) gene may lead to altered COX-2 production and/or activity, resulting in interindividual differences in susceptibility to pancreatic cancer. To test this hypothesis, we investigated the relationship between polymorphisms in the COX-2 gene and the risk of pancreatic cancer in a European population.