Cyclooxygenase-2 Polymorphisms and Pancreatic Cancer Susceptibility


Ozhan G. , Lochan R., Leathart J. B. S. , Charnley R., Daly A. K.

PANCREAS, cilt.40, sa.8, ss.1289-1294, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Konu: 8
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1097/mpa.0b013e31821fcc3b
  • Dergi Adı: PANCREAS
  • Sayfa Sayıları: ss.1289-1294

Özet

Objectives: DNA sequence variants in the cyclooxygenase-2 (COX-2) gene may lead to altered COX-2 production and/or activity, resulting in interindividual differences in susceptibility to pancreatic cancer. To test this hypothesis, we investigated the relationship between polymorphisms in the COX-2 gene and the risk of pancreatic cancer in a European population.