Voxel-Based Morphometry of Optimistic and Pessimistic Brains: A Detailed Study Focusing on Age Range and Gender


Black Sea Journal of Engineering and Science, vol.7, no.2, pp.223-236, 2024 (Peer-Reviewed Journal) identifier


The aim of the present study was to investigate brain volumes in pessimist and optimist participants. Therefore, in the present voxel-based morphometry research, it is investigated whether optimism has a corresponding counterpart in the structure of the brain. Thirty-two participants were screened via a publicly available dataset to test for this. The participants are divided into two groups: low optimists and high optimists, each with sixteen people. In comparison, a significant difference (P<0.05) was not found between the groups we created as a result of statistical calculations; however, statistically significant results (P<0.001) were obtained via a detailed VBM analysis in many brain regions, especially the thalamus, amygdala, left insula, superior frontal gyrus, and right cerebellum regions. These differences were identified and reported.