Impact of Nail Psoriasis on Quality of Life: A Turkish Validation Study of NPQ-10 and NAPPA


ALTAN FERHATOĞLU Z., Zengin M., Yildirim G., ENGİN B., Serdaroglu S., Goktay F.

SKIN APPENDAGE DISORDERS, 2026 (ESCI, Scopus) identifier identifier

  • Publication Type: Article / Article
  • Publication Date: 2026
  • Doi Number: 10.1159/000550467
  • Journal Name: SKIN APPENDAGE DISORDERS
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, EMBASE
  • Istanbul University Affiliated: Yes

Abstract

Introduction: Nail psoriasis significantly impairs quality of life (QoL). General dermatology instruments often lack sensitivity for specific nail-related burdens. This study aimed to validate the Turkish versions of the Nail Psoriasis Quality of Life Scale (NPQ-10) and the Nail Assessment in Psoriasis and Psoriatic Arthritis (NAPPA). Methods: This cross-sectional validation study included 71 patients (42 male, 29 female). The questionnaires were translated into Turkish following international guidelines. Reliability and validity were assessed by analyzing correlations with the Dermatology Life Quality Index (DLQI) and clinical parameters (PASI, NAPSI). Results: The sample showed a male predominance (59.2%). DLQI scores showed a moderate positive correlation with NPQ-10 (r = 0.453) and NAPPA-QoL (r = 0.477). Patients with toenail involvement had significantly higher QoL impairment. While men had higher clinical severity scores (PASI), women reported higher stigma-related scores. Conclusion: The Turkish versions of NPQ-10 and NAPPA are valid and reliable instruments. They capture specific physical and psychosocial burdens of nail psoriasis more accurately than general tools, particularly regarding toenail involvement and stigma. Incorporating these tools into practice is recommended.