Low-dose natural human interferon-alpha lozenges in the treatment of Behcet's syndrome

Kilic H., Zeytin H. E., KORKMAZ C., Mat C., Gül A., Cosan F., ...More

RHEUMATOLOGY, vol.48, no.11, pp.1388-1391, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 11
  • Publication Date: 2009
  • Doi Number: 10.1093/rheumatology/kep237
  • Journal Name: RHEUMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1388-1391
  • Keywords: Behcet's syndrome, Oral ulcers, Low-dose oral interferon-alpha, SJOGRENS-SYNDROME, DISEASE, TRIAL
  • Istanbul University Affiliated: Yes

Abstract

Objectives. There had been evidence that low-dose local IFN could be beneficial in the management of recurrent oral ulcers (OUs). We investigated the efficacy and collected initial data on the safety of low-dose natural human IFN-alpha administered by the oral mucosal route in Behcet's syndrome (BS) in a placebo controlled, double blind study.