Is there any correlation between TNF-related adoptosis-inducing ligand (TRAIL) genetic variants and breast cancer?

Yildiz Y., Yaylim-Eraltan I., Arıkan S., Ergen H. A., Kucucuk S., Isbir T.

ARCHIVES OF MEDICAL SCIENCE, cilt.6, sa.6, ss.932-936, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6 Sayı: 6
  • Basım Tarihi: 2010
  • Doi Numarası: 10.5114/aoms.2010.19304
  • Dergi Adı: ARCHIVES OF MEDICAL SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.932-936
  • Anahtar Kelimeler: TRAIL, breast cancer, susceptibility, prognosis, polymorphism, INDUCED APOPTOSIS, MULTIPLE-SCLEROSIS, RECEPTOR FAMILY, CELL-LINES, IDENTIFICATION, CHEMOTHERAPY, POLYMORPHISM, MEMBER, APO2L/TRAIL, CLONING
  • İstanbul Üniversitesi Adresli: Evet

Özet

Introduction: TNF-related apoptosis-inducing ligand (TRAIL) is a death ligand and also a member of the TNF superfamily. We aimed to investigate the possible relationship between TRAIL and breast cancer. Here, we report the results of the first association study on genetic variation in the TRAIL gene and its effect on breast cancer susceptibility and prognosis.