TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.17, no.5, pp.474-479, 2020 (ESCI)
Article / Article
TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, International Pharmaceutical Abstracts, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
Acetamiprid, AR42J pancreatic cell line, cytotoxicity, genotoxicity, oxidative damage, IN-VITRO, OXIDATIVE STRESS, COMET ASSAY, LYMPHOCYTES, PESTICIDES, TOXICITY, EXPOSURE, HEALTH
Istanbul University Affiliated:
Objectives: Neonicotinoid insecticides, 30% of insecticides marketed worldwide, have selective toxicity on insects through alpha 4p2 nicotinic acetylcholine receptors. Although it is known that acetamiprid exerts toxicity on several organ systems, its toxic effects on the pancreas and its mechanism of action have not been clarified yet. Therefore, in the present study, the cytotoxic and genotoxic potentials of acetamiprid on the AR42J pancreatic cell line were evaluated.