Acquired FVIII and FIX Inhibitors after Pregnancy: A Case Report.

Kose M., Bakkaloglu O. K., Amikishiyev S., Akpinar T. S., Saracoglu B., Akcan T., ...Daha Fazla

Acta haematologica, cilt.136, sa.4, ss.229-232, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 136 Sayı: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1159/000445706
  • Dergi Adı: Acta haematologica
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.229-232
  • Anahtar Kelimeler: Acquired hemophilia, Autoantibodies, FVIII and FIX inhibitors, FACTOR-VIII, HEMOPHILIA-A, FACTOR-IX, THERAPY, PATIENT
  • İstanbul Üniversitesi Adresli: Evet

Özet

Acquired hemophilia is a relatively rare clinical presentation, and most cases present with acquired FVIII inhibitor. The co-occurrence of inhibitors to multiple coagulation factors is uncommon. These autoantibodies may induce spontaneous life-threatening bleeding in patients who have had no previous bleeding disorder. Herein, we present a patient with postpartum acquired FVIII and FIX inhibitors who developed intramuscular hematoma and hemothorax during follow-up. She was then treated with activated prothrombin complex concentrate and methylprednisolone. (C) 2016 S. Karger AG, Basel