Acquired FVIII and FIX Inhibitors after Pregnancy: A Case Report

Kose M. , Bakkaloglu O. K. , Amikishiyev S. , Akpinar T. S. , Saracoglu B., Akcan T., ...Daha Fazla

ACTA HAEMATOLOGICA, cilt.136, ss.229-232, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 136 Konu: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1159/000445706
  • Sayfa Sayıları: ss.229-232


Acquired hemophilia is a relatively rare clinical presentation, and most cases present with acquired FVIII inhibitor. The co-occurrence of inhibitors to multiple coagulation factors is uncommon. These autoantibodies may induce spontaneous life-threatening bleeding in patients who have had no previous bleeding disorder. Herein, we present a patient with postpartum acquired FVIII and FIX inhibitors who developed intramuscular hematoma and hemothorax during follow-up. She was then treated with activated prothrombin complex concentrate and methylprednisolone. (C) 2016 S. Karger AG, Basel