Effects of Ganoderma lucidum on Obstructive Jaundice-induced Oxidative Stress

Aydin S., Aytac E., Uzun H., Altug T., Mansur B., Saygili S., ...More

ASIAN JOURNAL OF SURGERY, vol.33, no.4, pp.173-180, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 4
  • Publication Date: 2010
  • Doi Number: 10.1016/s1015-9584(11)60003-1
  • Journal Name: ASIAN JOURNAL OF SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.173-180
  • Istanbul University Affiliated: Yes

Abstract

OBJECTIVE: Obstructive jaundice develops after occlusion of the common bile duct. Direct hyperbilirubinaemia, which occurs secondary to the condition, causes various life-threatening pathologies. Cytoprotective effects of Ganoderma lucidum (GL) have previously been shown. In this study, the effects of GL on oxidative stress and oxidant DNA damage in experimental obstructive jaundice were evaluated.