The effects of sildenafil citrate on ischemic colonic anastomotic healing in rats: Its relationship between nitric oxide and oxidative stress

Uzun H., Konukoglu D., Nuri M. K., Ersoy E. Y., Ozcevik S., Yavuz N.

WORLD JOURNAL OF SURGERY, cilt.32, sa.9, ss.2107-2113, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 9
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1007/s00268-008-9661-2
  • Dergi Adı: WORLD JOURNAL OF SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2107-2113
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background The purpose of this study was to examine the effects of sildenafil citrate on normal and ischemic colon anastomosis in the rat model by measuring the levels of blood and colonic tissues nitric oxide, thiobarbituric acid reactive substrates (as a marker of lipid peroxidation), and glutathione (as an antioxidant).