Role of mir-33a, mir-203b, mir361-3p, and mir-424 in hepatocellular carcinoma

Yalcinkaya B., Guzel Tanoglu E., Tastekin D., Pence S.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.51, no.2, pp.638-643, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.3906/sag-2004-214
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.638-643
  • Istanbul University Affiliated: Yes

Abstract

Background/aim: Hepatocellular carcinoma (HCC) is one of the most aggressive cancer types. MicroRNAs (miRNAs) are small noncoding regulatory RNAs that function posttranscriptionally. miRNA deregulation was observed in the development and progression of HCC. In this study, we aimed to investigate the expression levels of four miRNAs (mir-33a, mir-203b, mir361-3p, and mir-424) in HCC patients in comparison to healthy individuals.