Clinical and Demographic Characteristics of Pediatric Patients With Psoriasis: Age-Related Variations and Remission Predictors
PEDIATRIC DERMATOLOGY, cilt.43, sa.1, ss.79-83, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 43 Sayı: 1
- Basım Tarihi: 2026
- Doi Numarası: 10.1111/pde.16043
- Dergi Adı: PEDIATRIC DERMATOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
- Sayfa Sayıları: ss.79-83
- İstanbul Üniversitesi Adresli: Hayır
Özet
This retrospective study of 110 pediatric patients with psoriasis identified significant age-related variations in the clinical presentation and key predictors of remission. The prevalence of chronic plaque psoriasis increased with age, whereas guttate psoriasis, which is strongly associated with elevated ASO titers, was more common in younger children. The median time to remission progressively increases with age. Older age (>= 11 years), chronic plaque morphology, higher baseline PASI scores (>= 10), and nail involvement were independent predictors of longer time to remission. Conversely, biologic therapy and methotrexate were associated with a shorter time to remission. The findings of this study suggest that high-risk pediatric patients should be identified and treated with early systemic therapy.