Memantine and Q-VD-OPh Treatments in Experimental Spinal Cord Injury: Combined Inhibition of Necrosis and Apoptosis

Aydoseli, AYDIN; Can, Halil; Aras, YAVUZ; Sabanci, PULAT; Akcakaya, Mehmet; Unal, Omer

doi:10.5137/1019-5149.jtn.12999-14.1

Memantine and Q-VD-OPh Treatments in Experimental Spinal Cord Injury: Combined Inhibition of Necrosis and Apoptosis

Aydoseli A., Can H., Aras Y., Sabanci P. A., Akcakaya M. O., Unal O. F.

TURKISH NEUROSURGERY, vol.26, no.5, pp.783-789, 2016 (SCI-Expanded, Scopus, TRDizin)

Publication Type: Article / Article
Volume: 26 Issue: 5
Publication Date: 2016
Doi Number: 10.5137/1019-5149.jtn.12999-14.1
Journal Name: TURKISH NEUROSURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Page Numbers: pp.783-789
Keywords: Spinal cord injury, Q-VD-OPh, Apoptosis, Memantine, Necrosis, Neuroprotection, FOCAL CEREBRAL-ISCHEMIA, MAGNESIUM-SULFATE, RECEPTOR ANTAGONIST, CASPASE INHIBITOR, FUNCTIONAL-ROLE, AMINO-ACIDS, RAT, RECOVERY, DEATH, IMPROVES
Istanbul University Affiliated: Yes

Abstract

AIM: To evaluate the effects of NMDA receptor antagonist memantine and pancaspase inhibitor Q-VD-Oph in combination or alone in experimental spinal cord injury.