Memantine and Q-VD-OPh Treatments in Experimental Spinal Cord Injury: Combined Inhibition of Necrosis and Apoptosis


Aydoseli A. , Can H. , Aras Y. , Sabanci P. A. , Akcakaya M. O. , Unal O. F.

TURKISH NEUROSURGERY, vol.26, no.5, pp.783-789, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.5137/1019-5149.jtn.12999-14.1
  • Journal Name: TURKISH NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded, Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.783-789
  • Keywords: Spinal cord injury, Q-VD-OPh, Apoptosis, Memantine, Necrosis, Neuroprotection, FOCAL CEREBRAL-ISCHEMIA, MAGNESIUM-SULFATE, RECEPTOR ANTAGONIST, CASPASE INHIBITOR, FUNCTIONAL-ROLE, AMINO-ACIDS, RAT, RECOVERY, DEATH, IMPROVES

Abstract

AIM: To evaluate the effects of NMDA receptor antagonist memantine and pancaspase inhibitor Q-VD-Oph in combination or alone in experimental spinal cord injury.