Memantine and Q-VD-OPh Treatments in Experimental Spinal Cord Injury: Combined Inhibition of Necrosis and Apoptosis

Aydoseli, AYDIN; Can, Halil; Aras, YAVUZ; Sabanci, PULAT; Akcakaya, Mehmet; Unal, Omer

doi:10.5137/1019-5149.jtn.12999-14.1

Memantine and Q-VD-OPh Treatments in Experimental Spinal Cord Injury: Combined Inhibition of Necrosis and Apoptosis

Aydoseli A., Can H., Aras Y., Sabanci P. A., Akcakaya M. O., Unal O. F.

TURKISH NEUROSURGERY, cilt.26, sa.5, ss.783-789, 2016 (SCI-Expanded, Scopus, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 26 Sayı: 5
Basım Tarihi: 2016
Doi Numarası: 10.5137/1019-5149.jtn.12999-14.1
Dergi Adı: TURKISH NEUROSURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.783-789
Anahtar Kelimeler: Spinal cord injury, Q-VD-OPh, Apoptosis, Memantine, Necrosis, Neuroprotection, FOCAL CEREBRAL-ISCHEMIA, MAGNESIUM-SULFATE, RECEPTOR ANTAGONIST, CASPASE INHIBITOR, FUNCTIONAL-ROLE, AMINO-ACIDS, RAT, RECOVERY, DEATH, IMPROVES
İstanbul Üniversitesi Adresli: Evet

Özet

AIM: To evaluate the effects of NMDA receptor antagonist memantine and pancaspase inhibitor Q-VD-Oph in combination or alone in experimental spinal cord injury.