Akademik Veri Yönetim Sistemi
12th International Congress of the European Union Geriatric Medicine Society, Lisbon, Portekiz, 5 - 07 Ekim 2016, cilt.7, sa.1, ss.7
Aim: For sarcopenic low muscle mass definition, different muscle mass assesment methods and units have been suggested by different groups. Baumgartner et al. suggest measurement of muscle mass in unit height (kg/m2 ), Janssen et al. suggest muscle mass in unit total body weight (%) FNIH group suggest muscle mass in unit body mass index (BMI). The most common application in literature for sarcopenic muscle mass is Baumgartner definition, although in the last years it’s suggested that other muscle mass units may be more successfull for predicting sarcopenic muscle mass. In this study, determination of sarcopenic cut-off points associated with Janssen and FNIH definitions was targeted.
Methods: Healthy young adults between 18 and 39 years of age with no known chronic disease and chronic drug usage and elder individuals Community-dwelling, at 60–99 years of age were included into the study. Body composition was assessed with bioimpedance analysis (BIA) using a Tanita BC 532 model body analysis monitor. Sarcopenic muscle mass was defined as a mean of −1 SD (class 1 sarcopenia) from the healthy young adults muscle mass value and a mean of −2 SD(class 2 sarcopenia) for Janssen definition; mean −2 SD for FNIH definitiation. In addition, as suggestied by FNIH, muscle mass cut-off point in elder people that predicts low muscle strength was calculated with ROC analysis. Low muscle strength cut-off points were <32 kg, for men, and <22 kg for women according to national data.
Results: 301 Healthy young adults (187 male,114 female) and 992 elder individuals were included into the study. Mean age for young adult reference group was 26,5 ± 4,6 years and mean age for older adults was 74,7 ± 7,1 yıl. (SMMI index was 11 ± 0,9 ve 9 ± 0.8 kg/m2 in young adults and 10,9 ± 1,1 and 10,1 ± 1,2 kg/m2 in older subjects) Class 1 sarcopenia cut-off points were %40,4 and %37,2 respectively for male and female acording to Janssen definition; class 2 sarcopenia cut-off point were %37,4 and %33,6 (table). for males cutpoint was 1,05 kg/ BMI; for female 0,82 kg/BMI acording to FNIH defination. The muscle mass cut-off point that best predicts the low grip strength was 1,02 kg/ BMI for males, 0,68 kg/BMI for females associated FNIH definition.
Conclusion: Sarcopenic muscle mass cut-off points, muscle mass
assesment methods and values show diversity. Muscle mass cut-off
points that were detected by other units were higher in Turkish
population than other populations as like muscle mass cut-off points
in our study that were associated with Baumgartner (kg/m2
) suggested
by EWGSOP.