miR-421, miR-155 and miR-650: Emerging Trends of Regulation of Cancer and Apoptosis

FAROOQI A. A., QURESHI M. Z., Coskunpinar E., NAQVI S. K., Yaylim I., ISMAIL M.

ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, cilt.15, sa.5, ss.1909-1912, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 15 Sayı: 5
  • Basım Tarihi: 2014
  • Doi Numarası: 10.7314/apjcp.2014.15.5.1909
  • Dergi Adı: ASIAN PACIFIC JOURNAL OF CANCER PREVENTION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1909-1912
  • Anahtar Kelimeler: miRNA, cancer, apoptosis, signaling, FARNESOID X RECEPTOR, UP-REGULATION, MICRORNA-155 PROMOTES, CELL-PROLIFERATION, DOWN-REGULATION, EXPRESSION, CARCINOMA, MIRNA, OVEREXPRESSION, CONTRIBUTES
  • İstanbul Üniversitesi Adresli: Evet

Özet

It is becoming progressively more understandable that between transcription and translation there lies another versatile regulator that quantitatively controls the expression of mRNAs. Identification of miRNAs as key regulators of wide ranging signaling cascades and modulators of different cell-type and context dependent activities attracted basic and clinical scientists to study modes and mechanisms in details. In line with this approach overwhelmingly increasing in vivo and in vitro studies are deepening our understanding regarding miR-421, mir-155 and miR-650 mediated regulation of cellular activities. We also attempt to provide an overview of long non coding RNAs.