Nitric oxide mediated effects of nebivolol in myocardial infarction: the source of nitric oxide.

Mercanoglu G., Safran N., Ahishali B. B., Uzun H., Yalcin A., Mercanoglu F.

European review for medical and pharmacological sciences, cilt.19, sa.24, ss.4872-89, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 24
  • Basım Tarihi: 2015
  • Dergi Adı: European review for medical and pharmacological sciences
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.4872-89
  • Anahtar Kelimeler: Myocardial infarction, Nebivolol, Nitric oxide, Nitric oxide synthase, REPERFUSION INJURY, SYNTHASE, HEART, RATS, EXPRESSION, ISCHEMIA, CYCLASE, STRESS, OXYGEN
  • İstanbul Üniversitesi Adresli: Evet

Özet

OBJECTIVE: After MI pathological LV remodeling is one of the major causes of death. We previously showed the NO mediated beneficial effects of nebivolol in rat MI model, in this study we aimed to evaluate the NOS related mechanisms in this phenomenon.