Nitric oxide mediated effects of nebivolol in myocardial infarction: the source of nitric oxide.


Mercanoglu G., Safran N., Ahishali B. B., Uzun H., Yalcin A., Mercanoglu F.

European review for medical and pharmacological sciences, vol.19, no.24, pp.4872-89, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 24
  • Publication Date: 2015
  • Journal Name: European review for medical and pharmacological sciences
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.4872-89
  • Keywords: Myocardial infarction, Nebivolol, Nitric oxide, Nitric oxide synthase, REPERFUSION INJURY, SYNTHASE, HEART, RATS, EXPRESSION, ISCHEMIA, CYCLASE, STRESS, OXYGEN
  • Istanbul University Affiliated: Yes

Abstract

OBJECTIVE: After MI pathological LV remodeling is one of the major causes of death. We previously showed the NO mediated beneficial effects of nebivolol in rat MI model, in this study we aimed to evaluate the NOS related mechanisms in this phenomenon.