Akademik Veri Yönetim Sistemi
36th europen congress of pathology, Florence, İtalya, 7 - 11 Eylül 2024, ss.27-28
Background & objectives: The orbital region encompasses muscles,
nerves, adipose tissue, vascular structures, lacrimal glands; rendering
it susceptible to various pathological entities including inflammatory
lesions, cysts and tumours. Neoplastic lesions manifest as primary or
secondary involvement. This study aims to analyze frequency of such
lesions using data obtained from tertiary care centre.
Methods: Between 2007 and 2024, a total of 614 orbital lesions were
identified. Repeated biopsies from the same patients were excluded
from the analysis, with only the most recent resection material considered. Orbital lesions were categorized as: neoplastic and non-neoplastic. Neoplastic lesions were further subcategorized as primary tumours
and secondary involvement.
Results: The mean age of the study group was 26 years(range: 1-93).
Out of 614 cases,327 were male and 287 were female.116 patients
were under 18 years of age. Among adults, neoplastic lesions(63%)
were more common, while non-neoplastic lesions including cysts and
inflammatory lesions(53%) prevailed among children. The most frequent cystic lesion was dermoid cyst. Neoplastic lesions comprised
mesenchymal tumours, lymphomas, salivary gland tumours, metastatic
tumours, and secondary infiltration from surrounding areas. Mesenchymal tumours were the most frequent lesions regardless of age, with
hemangioma being the most common in adults, while rhabdomyosarcoma predominated in children. Lymphomas, mostly low-grade,
followed mesenchymal tumours in frequency. Primary salivary gland tumours originating from the lacrimal gland were also identified, with
the most common subtype being pleomorphic adenoma.
Conclusion: Our analysis of orbital lesions revealed varied prevalence
of neoplastic and non-neoplastic entities across different age groups.
Neoplastic lesions, predominantly mesenchymal tumours, lymphomas,
and salivary gland tumours, exhibited varied prevalence across different age groups, with hemangioma and rhabdomyosarcoma emerging
as predominant subtypes in adults and children, respectively. Nonneoplastic inflammatory lesions, notably cysts, were prevalent among
paediatric patients. These results highlight the heterogeneous distribution of the orbital lesions.