Osteointegration of a Bisphenol-a-Glycidyl-Dimethacrylate Composite and Its Use in Anterior Skull Base Defects: An Experimental Study in an Experimental Design Model of Cerebrospinal Fluid Leak

Sanus G. Z. , Kucukyuruk B., Biceroglu H., Isler C. , Tanriverdi T. , Bas A., ...More

JOURNAL OF CRANIOFACIAL SURGERY, vol.25, no.4, pp.1524-1528, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 4
  • Publication Date: 2014
  • Doi Number: 10.1097/scs.0000000000000962
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1524-1528


Object: Promising clinical results were reported in watertight closure of anterior skull base defects (ASBDs) with bisphenol-a-glycidyl-dimethacrylate (bis-GMA)-based materials to prevent the cerebrospinal fluid leaks. However, interrelation of these materials with surrounding bones in histologic level, referred to as the osteo-integration, has not been reported in the anterior skull base. In addition, an illustrative case with an ASBD that was repaired using a bis-GMA composite has been presented.